Evaluation of air pollution genotoxic effects in children by the buccal micronucleus cytome assay
نویسندگان
چکیده
منابع مشابه
Genetic damage in coal miners evaluated by buccal micronucleus cytome assay.
During coal mining activities, large quantities of coal dust, ashes, polycyclic aromatic hydrocarbons and metals are released into the environment. This complex mixture presents one of the most important occupational hazards for health of workers. The aim of the present study was to evaluate the genetic damage together with the presence of inorganic elements, in an exposed workers population to...
متن کاملRadiation risk assessment in professionals working in dental radiology area using buccal micronucleus cytome assay.
OBJECTIVE The aim of this study was to assess the incidence of micronuclei (MN) in buccal mucosal cells of professionals working in radiology area to determine the risk of stochastic effects of radiation. MATERIALS AND METHODS All the professionals and students working in King Khalid University - College of Dentistry radiology area were included in the Risk Group (RG = 27). The Control Group ...
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Cumulative exposure to oestrogen has been linked to increased risk of breast cancer. Whilst oestrogens induce cancers in rodent bioassays it is unclear whether the mechanisms involved are genotoxic and/or epigenetic. The cytokinesis block micronucleus (CBMN) and the alkaline single cell-gel electrophoresis 'Comet' assays were used to examine MCF-7 cells for chromosomal damage and DNA single-str...
متن کاملGenotoxic and Antigenotoxic Activity of Silymarin by an In Vivo Bone Marrow Micronucleus Assay and Comet Assay
Introduction: Silymarin is obtained from Silybum marianum (milk thistle), an edible plant that has long been used medicinally for the treatment of liver-related disorders. Silymarin is a powerful hepatoprotective and antioxidant but the anticlastogenic activity, which is an important aspect of its cancer chemoprevention is not known hence the present investigation was carried out to study its...
متن کاملTesting chemical agents with the cytokinesis-block micronucleus cytome assay.
In order to evaluate the applicability of the cytokinesis-block micronucleus cytome assay in routine mutagenicity testing we investigated with this method different chemicals having different mechanisms of action: non-mutagens, direct-acting basealtering mutagens, direct-acting cross-linking mutagens, clastogens including a radiomimeti...
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ژورنال
عنوان ژورنال: European Journal of Public Health
سال: 2015
ISSN: 1464-360X,1101-1262
DOI: 10.1093/eurpub/ckv176.238